Home  Contact Us
  Follow Us On:
 
Search:
Advertising Advertising Free Newsletter Free E-Newsletter
NEWS

COVID-19 patients with diarrhea more likely to have severe symptoms
Published on: 2020-04-23
Share to
User Rating: / 0
PoorBest 

patientResearchers have found that more novel coronavirus disease (COVID-19) patients with diarrhea showed severe symptoms of pneumonia than those without diarrhea, according to a recently published research article in the journal Lancet Gastroenterology and Hepatology.
 

The researchers from the Sixth Affiliated Hospital of Sun Yat-sen University and its Research Institute of Gastroenterology examined the intestinal symptoms of patients with COVID-19 from multiple medical centers in China.

34a56a7e 4d2d 4633 8470 b8717411dc83They collected and analyzed data from 232 patients who were tested positive for COVID-19 and admitted to 14 hospitals in provinces of Guangdong, Hubei and Jiangxi from January 19 to March 6. Two patients with pre-existing digestive diseases were excluded from the analysis.
 

The patients' most common symptoms at the onset of illness were fever, cough and sputum production. Diarrhea was observed in 49 patients, or 21 percent, according to the research article which said that the patients with diarrhea were older and more likely to have comorbidities than those without diarrhea.
 

The researchers also discovered that more patients with diarrhea showed severe symptoms of pneumonia than those without. Although there was no correlation between diarrhea and oxygen supplementation, a greater proportion of patients with diarrhea required ventilator support and admission to intensive care, said the article.

e81cfe6d 3898 426f 818c ce617dec8f73They did not observe a correlation between diarrhea and the use of antiviral medicine or antibiotics.
 

The analysis did not cover the data on the prevalence of asymptomatic COVID-19.
 

The researchers also pointed out that the medicines like antivirals, lopinavir and ritonavir are known to cause diarrhoea.
 

新冠肺炎患者出现胃肠症状更易发展为重症

新冠肺炎患者若出现胃肠症状将有更高几率发展为重症。中山大学附属第六医院兰平教授团队在《柳叶刀》胃肠病和肝病子刊上,针对“武汉以外新冠肺炎住院患者的胃肠症状”发表了一项关于新型冠状病毒的胃肠道症状原创研究论文,此项多中心回顾性研究由中山六院、中山大学胃肠病学研究所和全国多家医院及研究机构合作完成。
 

虽然新冠病毒引起的疾病名称是肺炎,但该病毒的受体在全身几乎所有组织中都有表达,尤其在胃肠道有很高的表达。“假如忽略胃肠症状,将有可能阻碍部分新冠病人的确诊,并加剧病毒经粪口传播的危害。”兰平说。基于此,团队和湖北、广东、江西的多个医院建立了合作关系,收集了232位匿名新冠病人的病历。在研究中发现,21%的新冠病毒感染者在住院期间出现了腹泻症状,大大高于原先报道中的3%。同时,还发现很多新冠病毒感染患者有血便的症状。这些结果均支持了新冠病毒经由消化道的传播机制。

Comments (0)Add Comment

Write comment

security code
Write the displayed characters


busy
    Subscription    |     Advertising    |     Contact Us    |
Address: Magnetic Plaza, Building A4, 6th Floor, Binshui Xi Dao.
Nankai District. 300381 TIANJIN. PR CHINA
Tel: +86 22 23917700
E-mail: webmaster@businesstianjin.com
Copyright 2024 BusinessTianjin.com. All rights reserved.