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Whether Recovered Covid-19 Patients Are Immune
Published on: 2020-06-24
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Medical researchers say the China coronavirus may be present in patients displaying no outward signs of illness

Medical researchers say the China coronavirus may be present in patients displaying no outward signs of illness

A new study conducted by Chinese experts found Covid-19 antibodies may start to diminish within two or three months in most asymptomatic and symptomatic patients after they are initially infected, raising doubts over whether antibodies could serve as “immunity passports” for people who have recovered from the illness.
 

The study published by Nature Medicine on June 18, performed by a team from Chongqing Medical University, also found that asymptomatic people had a weaker immune response to Covid-19 infections than those who had symptoms.
 

The researchers compared the immune responses of 37 asymptomatic individuals and 37 symptomatic patients and found 40% of the asymptomatic group gave a negative result in a test of blood serum for immunoglobulin G antibodies eight weeks after being discharged from the hospital, while the number for symptomatic group only stood at 12.9%.
 

The authors said in the paper, “Together, these data might indicate the risks of using COVID-19 ‘immunity passports’ and support the prolongation of public health interventions, including social distancing, hygiene, isolation of high-risk groups and widespread testing.”
 

No consensus has been made on how long and to what extent antibodies can protect people. The World Health Organization released a scientific briefing in April warning that “there is currently no evidence that people who have recovered from COVID-19 and have antibodies are protected from a second infection.”
 

新冠患者康复后,抗体很快就消失!有人已感染第二次!

中国研究人员日前在英国《自然•医学》杂志上发表的一项研究显示,他们在重庆市进行的调查发现,新冠病毒感染者痊愈后体内抗体水平会迅速下降。此外,无症状感染者的免疫反应弱于有症状感染者。
 

报道称,大多数病毒感染者表现出相对轻微的感染症状,而一小部分人根本没有任何症状。
 

报道称,人们对这一人群知之甚少,因为他们接受检测的可能性远低于那些随后出现严重症状——包括呼吸系统问题——的人。
 

中国的研究人员对重庆万州区两组新冠肺炎病人进行了比较:37人表现出症状,37人没有。
 

研究人员对两组患者在康复数周后采集的血样进行了分析,结果发现,只有62.2%的无症状人群有短期抗体,而有症状患者有短期抗体的比例为78.4%。
 

报道称,经过八周的康复治疗,81.1%的无症状患者抗体水平下降,而有症状患者抗体水平下降的比例为62.2%。
 

此外,研究人员还发现,无症状患者比有症状患者的18种亲抗炎细胞信号蛋白质含量更低,表明他们对这种新型冠状病毒的免疫反应较弱。
 

发表在《自然•医学》杂志上的这项研究的作者说,他们的发现让人们对每个得过新冠病毒的人都能抵抗今后感染这一观点产生了怀疑。
 

他们写道:“这些数据可能表明了使用新冠肺炎‘免疫护照’的风险,并支持延长公共卫生干预措施,包括保持社交距离、讲究卫生、隔离高危人群和广泛检测。”
 

英国免疫学会发言人、帝国理工学院免疫学教授丹尼•奥尔特曼说,这项研究对抗击新冠肺炎提出了一个至关重要的问题。
 

他说:“迄今为止,免疫学的许多数据都来自对住院危重病人进行的分析,但大多数受影响较轻的人都想知道,这是否可能会带来持久的保护性免疫。”
 

奥尔特曼说,在研究中,许多患者在短短两个月内抗体水平就显著下降,这是“一个重要且可能令人担忧的问题”。
 

并未参与研究的奥尔特曼说:“尽管这个样本规模很小,但这与一些人的担忧是一致的,即新冠病毒的自然免疫力可能相当短暂。”

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