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Coronavirus May Pass From Mom to Baby
Published on: 2020-07-16
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baby 01Cases of transmission of COVID-19 from pregnant mothers to their babies are rare and should not spark undue concern, experts said on Tuesday after a case study was published suggesting the novel coronavirus may be able to cross the placenta.

The study, published in the journal Nature Communications, described a case in France where the COVID-19-causing virus was found in the blood of a baby born prematurely to a 23-year-old mother who was diagnosed with the pandemic disease in March.

The detection of the virus in placental tissue, as well as in the mother's and baby's blood, suggests that "transplacental transmission of SARS-CoV-2 (the virus that causes COVID-19) may be possible," the doctors detailing the case wrote. They added, however, that further studies would be needed to confirm this.

Marian Knight, a professor of maternal and child population health at Britain's Oxford University, said the case was interesting, but should not be a major worry for pregnant women.

"Among the many thousands of babies born to mothers with SARS-CoV-2 infection, a very few have been reported to also have a positive test – around 1-2%," she said. "It is still unclear whether the virus passes across the placenta; this report provides evidence that it may."

Both mother and baby in the French case recovered well and were discharged from hospital.

全球首例新冠母婴传播被证实

SARS-CoV-2(新冠病毒)检测呈阳性的母亲可能通过胎盘,将病毒传染给婴儿。来自法国的研究团体通过一项个案研究报告了相关证据,证明一名当地时间7月14日,国际学术期刊《自然-通讯》(Nature communications)在线发表了上述研究。

作者们指出,明确SARS-CoV-2是否及如何到达胎儿,对于预防新生儿感染、优化妊娠管理,最终更好地了解SARS-CoV-2的生物学意义重大。在这篇论文中,他们提供了一个全面的病例研究,证明SARS-CoV-2经胎盘传播,并且新生儿具有与SARS-CoV-2感染相关的神经学临床症状。

作者们认为,这些数据以及他们的研究结果结合起来可以证实,在妊娠的最后几周,SARS-CoV-2确实有可能通过胎盘传播。当然,他们也不能排除在妊娠早期可能的传播和胎儿影响,因为目前还没有确切的文献资料。

总的来说,作者们已经证明,SARS-CoV-2感染可能在妊娠的最后几周通过胎盘传播,经胎盘传播可引起胎盘炎症和新生儿病毒血症。神经影像学显示白质损伤,这可能是由SARS-CoV-2感染引起的血管炎症引起,在成人患者中也发现了类似的情况。

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