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Hebei virus strain may have originated from Russia
Published on: 2021-01-08
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The COVID-19 strains found in Hebei Province — where there has seen a rapid surge in cases — may have originated in Russia, according to a research paper published on China CDC Weekly.
 

Researchers analyzed the sequences of samples of two Hebei COVID-19 patients — one from the provincial capital Shijiazhuang and the other from Xingtai — and found the genomic characteristics of the strains differed from recent strains detected in China.
 

After accessing the public database GISAID and GenBank, three Russian strains detected in July were found to share 10 variation sites with the two Hebei strains. Three unique sites detected in the Russian strains were seen in the Hebei strains.
 

The two patients tested positive for the virus on January 2. Neither had traveled abroad before being diagnosed.

石家庄、邢台首例或源自俄罗斯毒株

1月6日,《China CDCweekly 》《中国疾病预防控制中心周报(英文)》刊发的中疾控与河北省疾控中心撰写的文章称,该中心1月2日对石家庄确诊病例(A)和邢台确诊病例(B)的样本进行基因组测序,结果显示,该毒株与我国既往已报道的输入性病例以及国内由输入导致的本土聚集性疫情的病毒的基因组不存在关联性,说明不是近期国内各地本土疫情导致的继发性传播,导致这起疫情的病毒溯源工作正在开展之中。
 

进一步分析得知,A和B样本高度相似,均属于L基因型欧洲家系分支I/B.1.1.123分支基因位点的突变特征,提示2个城市首例病例的病毒感染来源属于同一传播来源和同一传播链,且不含有南非新型毒株以及英国新型毒株的氨基酸关键性变异位点。在全球公开数据库检索发现,A与B的基因组序列与一些7月份上传的俄罗斯基因组序列存在10个相同的核苷酸变异位点。尽管共有变异位点较少,但从俄罗斯毒株中检测到的3个特异性位点仅在此次河北毒株中出现,病毒可能起源于该俄罗斯毒株。
 

“从病毒溯源结果看,病毒是境外输入病毒,但是否和机场相关,现在还没有从流行病学调查和环境检测中得到清晰的证据,还在调查当中。

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