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New evidence suggests coronavirus jumped from animals to humans multiple times
Published on: 2021-10-13
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A new pre-print study released online recently has provided strong evidence to support the "natural spillover" hypothesis on COVID-19, with results that are hard to reconcile with the "lab leak" hypothesis.
 

SARS-CoV-2, the virus that causes COVID-19, could have spilled from animals to people multiple times, according to the preliminary analysis of viral genomes sampled from people infected early in the pandemic.
 

The latest analysis, posted on the virological.org discussion forum, is based on a detailed examination of the genetic sequences of two early lineages, known as A and B, which have key genetic differences, obtained from people infected in late 2019 and early 2020.
 

"It is a very significant study ... If you can show that A and B are two separate lineages and there were two spillovers, it all but eliminates the idea that it came from a lab," a Nature news article quoted Robert Garry, a virologist at Tulane University in New Orleans, Louisiana, as saying.
 

新冠与动物的病毒有密不可分的关系

10月13日消息,据国外媒体报道,科学家对病毒基因组的初步分析表明,新冠病毒大流行可能存在源自动物的可能性,但这些发现仍需进一步验证。依据对部分国家和地区在疫情早期感染患者的病毒基因组样分析显示,新冠病毒可能曾多次从动物传播至人类。
 

一些研究人员表示,最早的新冠病毒序列取自2019年底和2020年初的感染患者,他们被分为两个谱系,被称为A谱系和B谱系,他们存在关键的遗传差异。
 

一个关键问题是这两种病毒谱系是如何发生关联的,如果A谱系病毒从B谱系病毒演变而来,或者情况相反,这就意味着原始病毒仅从动物传播至人类一次,但如果两种病毒谱系拥有不同的起源,那么可能会有更多的人畜共患的溢出传染事件。

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